In 1796 Dr. Edward Jenner performed an experiment that today would have
got him expelled from his Medical Society, and maybe even landed them
in jail. He vaccinated a boy against smallpox by pricking his arms with
pus taken from the sores of a milkmaid with cowpox, a closely related
but milder disease. He based this audacious experiment on his astute
observation that milkmaids, who had been exposed to cowpox, never
contracted smallpox. Let’s not forget what smallpox meant in those
days—it meant an almost 100% chance of death. Could anybody have
guessed that this observation would become the first harbinger of the
field of Immunology?
It took over 200 years before another vaccine was created; in 1914 a
vaccine against whooping cough was introduced. But then, the pace
picked up: in 1928 a vaccine against diphtheria, in 1933 against
tetanus, and so on. Five years ago a vaccine against varicella, causing
chickenpox and shingles was approved. Last year a vaccine against human
papilloma virus (HPV) was introduced. This virus causes endometrial
(lining of the uterus) cancer, and immunization of prepubertal girls
should protect them for life. This is the first successful vaccine
against cancer.
Robert Wachter is widely regarded as a leading figure in the modern
I am so so far behind getting my transcripts of podcasts up here that it’s not funny. But this was one of the most recent and one of the most fun that I’ve ever done. It was a discussion with Shannon Brownlee. author of
EDventure Holdings has agreed to serve on the
We also welcome David Kibbe MD MBA. A highly regarded figure in Washington and in healthcare information technology circles, Dr. Kibbe has served as director of the American Academy of Family Physicians’