Categories

Tag: Zelboraf

Rethinking Cancer Guidelines

Universal treatment standards will be the basis of future medical care.  In oncology, a leading organization for the development of such guidelines is the National Comprehensive Cancer Network (NCCN).  This national consortium of 21 National Cancer Institute designated cancer centers publishes state of the art recommendations.  Modified continuously, these are internationally respected guidelines and cover more then 97% of cancers.

The 17th Annual NCCN Conference was held in Hollywood, Florida last month. Cancer guidelines were updated in several significant ways.

The general movement of the last 20 years has been to reduce the amount of surgery for breast cancer. The NCCN recommends that during breast saving surgery (lumpectomy) the surgeon test the first lymph node (“sentinel”).  If there is no cancer in the first one or two nodes, then no more nodes need to be removed.  The NCCN also stated, that if breast cancer patients have small cancers and normal blood tests, they do not need a bone scan, or CT scan.

In lung cancer patients, several procedures received new support.  It is recommended that doctors use ultrasound-guided biopsy to sample lymph nodes in the middle of the chest (mediastinum) instead of surgery.  The new guidelines also support the use of non-invasive surgery (Video Assisted Thorascopic Surgery, VATS) instead of open surgery to treat lung cancer.  The use of VATS for lung cancer has increased more than 300% in recent years.  The pathologic name for an increasingly common form of lung cancer was changed.  Formally, called “bronchioalveolar”, it will now be called “adenocarcinoma in situ.”   Finally, the NCCN emphasized the need for accurate genetic testing for  “ALK”, before using the drug that targets this mutation, crizotinib.

Continue reading…

Registration

Forgotten Password?