The Wall Street Journal recently contacted me regarding an upcoming article on Sedasys, the new gadget that is supposed to be able to infuse propofol by computer while monitoring vital signs.
If you’ve read anything I’ve written previously, you’ll know that I am NOT a big proponent of technology as a means of “improving” patient care. To me, the more technology you put between the patient and the caregiver, the less medicine you’re practicing, and the more data-entry and computer programming you’re doing.
Sedasys is designed specifically to administer propofol. Propofol is a milk-like substance that produces a range of effects from sedation to general anesthesia. For sedation you just use less, for general anesthesia you use more. Its very quick onset and very quick recovery make it great for outpatient sedation. It has to be given in a continuous drip because its effect goes away so fast. GI docs love it because its so effective. I suspect they also love it because propofol comes with an anesthesiologist to give it.
The only problem is the one Michael Jackson encountered: it has this pesky side effect of causing you to stop breathing. And you can’t tell by looking at a person how much will sedate them and how much will make them stop breathing.
A little old lady with a million health problems might sedate at, say, 40 mg and stop breathing at 60 mg, while an 19-year-old could probably take 150 mg and still be fighting you. It’s not necessarily weight-based.